In my setup, the Nano Big Muff goes into a Weehbo JCM Drive (the blue one), with a Tube Screamer in front of it. This combination creates a versatile and dynamic range of tones. With the Sustain knob on the Nano Big Muff set almost off, I achieve a tight, focused fuzz that complements the overdrive from the Tube Screamer and the nuanced drive from the JCM Drive. This setup allows for a smooth transition from a gritty, aggressive fuzz to a more controlled and articulate distortion, perfect for both rhythm and lead playing.