I get my core tones, both live and in the studio, from a quality tube amp and various pedals - mostly drives and reverb/delay. The Helix HX extends this setup perfectly, giving me fantastic routing options, noise control, channel/preset switching on stage and killer modulation effects that I use too rarely to justify individual pedals for.
The Helix also hosts impulse responses (great sounding) so you can go straight to the PA. Even the modeled dirt pedals of the Helix generally sounds great pushing a real tube amp.
Super easy to use interface directly on the device, and even better with a USB connection to a computer using the free software editor.
Fantastic little device. Cannot recommend it enough